Endocrine Abstracts

Introduction: Impaired glucose tolerance and diabetes mellitus are frequently seen complications of acromegaly. Insulin resistance due to chronic growth hormone (GH) excess and inhibition of insulin and glucagon secretion by long-acting somatostatin analogues (SA) used in the treatment are the main reasons of the impaired glucose tolerance.Objective: To determine the effect of long-acting SA treatment on glucose homeostasis regarding the insulin resistan...